MyBioSource.com's [KD Validated] MAD1/MAD1L1 Rabbit pAb is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The [KD Validated] MAD1/MAD1L1 Rabbit pAb Antibody was generated using STE20 related adaptor alpha as the antigen and it reacts with Human.
Description
MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Alternative splicing results in multiple transcript variants